Depo-Provera Class Action Lawsuit 2025: A growing wave of lawsuits is targeting pharmaceutical giant Pfizer Inc., as thousands of women across the United States allege that long-term use of Depo-Provera—a widely prescribed birth control shot—has caused them to develop meningioma brain tumors and other severe health complications. As of 2025, all federal cases have been consolidated into a Multi-District Litigation (MDL No. 3140), overseen by Judge M. Casey Rodgers in the Northern District of Florida. With increasing media attention and mounting scientific evidence, this lawsuit is shaping up to become a landmark case in pharmaceutical litigation. If you or a loved one has been affected, here’s a complete guide to the Depo-Provera brain tumor lawsuit, including eligibility, how to file a claim, potential settlement payouts, and key legal milestones.
What Is the Depo-Provera Lawsuit About?
Depo-Provera (medroxyprogesterone acetate) is a long-acting hormonal contraceptive administered by injection every three months. While it’s been used for decades for birth control and menstrual suppression, recent studies have linked long-term use of the drug to the development of intracranial meningiomas—a type of tumor that forms in the membranes around the brain and spinal cord. Scientific research suggests that women who receive two or more Depo-Provera injections may face a significantly elevated risk of developing these tumors. Many women were reportedly unaware of this risk until they experienced symptoms like headaches, vision changes, or seizures—often leading to imaging scans, diagnosis, and even brain surgery. The lawsuits argue that Pfizer failed to adequately warn both patients and healthcare providers about the risks of long-term Depo-Provera use, despite growing evidence of a connection to serious neurological complications.
Who Is Eligible to File a Depo-Provera Brain Tumor Lawsuit?
You may qualify to file a Depo-Provera lawsuit or join MDL 3140 if you meet the following criteria:
- Received at least two Depo-Provera injections.
- Were diagnosed with a meningioma brain tumor after using the drug.
- Have medical records confirming both injection history and diagnosis.
- The diagnosis timing suggests a plausible link to Depo-Provera use.
Meeting these qualifications allows individuals to participate in the MDL or file a separate state claim. Keep in mind, however, that eligibility does not guarantee compensation—it simply enables participation in the litigation process.
How to File a Claim in the Depo-Provera MDL (MDL No. 3140)
Thanks to a recent ruling claimants from any U.S. state can now directly file into the centralized MDL court in Florida. Here’s how to get started:
- Consult an Attorney – Contact a law firm that specializes in pharmaceutical injury. Most offer free case evaluations.
- Collect Evidence – This includes injection history, medical records, brain imaging results, and symptom timelines.
- File Your Claim – Submit your complaint directly to MDL 3140.
- Complete Plaintiff Questionnaire – Document your Depo-Provera use and resulting meningioma diagnosis.
Once accepted into the MDL, your case will go through stages like discovery, expert testimony, and possibly trial or settlement.
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Expected Settlement Amounts in the Depo-Provera Class Action Lawsuit 2025
While a global settlement has yet to be reached, legal experts anticipate the following estimated payout ranges based on the severity of each case:
- Mild Injuries (No surgery or lasting impact):
$50,000 – $100,000 - Moderate Injuries (Surgery with recovery):
$100,000 – $250,000 - Severe Injuries (Disability or neurological damage):
$250,000 – $500,000+
Final settlement values may vary depending on factors like medical costs, emotional suffering, and lost income. The outcomes of early bellwether trials, scheduled to begin in early 2026, will heavily influence future compensation amounts.
New Health Complications Tied to Depo-Provera Class Action Lawsuit 2025
A recent case involving a 21-year-old woman who developed Phlegmasia Cerulea Dolens—a rare and life-threatening blood clot condition—after receiving Depo-Provera injections has raised additional concerns.
Although blood clots are listed as a potential side effect, the severity and sudden onset in otherwise healthy women suggest Pfizer may have failed to fully disclose these risks. This could bolster the argument that Depo-Provera carries more serious health consequences than previously acknowledged.
Important Points: Depo-Provera Class Action Lawsuit 2025 MDL Timeline
Here are the major upcoming dates in the Depo-Provera litigation process:
- May 11, 2025 – Pfizer completes general causation document production.
- July 25, 2025 – Discovery on preemption defenses ends.
- August 2025 – Summary judgment motions begin.
- February 2026 – Expert discovery concludes.
- Early to Mid-2026 – Bellwether trials commence.
These trials will be pivotal in determining whether Pfizer faces massive settlement payouts—or can defend the safety of Depo-Provera.
What to Do If You’ve Been Affected by Depo-Provera Class Action Lawsuit 2025
If you or a loved one has been diagnosed with a meningioma brain tumor after using Depo-Provera, now is the time to act. Speak with a qualified attorney to determine your legal options and secure your place in the MDL.
With litigation progressing quickly, potential settlement negotiations could begin by late 2025. Filing early helps ensure you meet court deadlines and preserve your right to compensation.
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Conclusion: Depo-Provera Class Action Lawsuit 2025
The Depo-Provera brain tumor lawsuit with thousands of women coming forward and scientific research reinforcing their claims, the pressure on Pfizer continues to mount. Whether through trial or settlement, this litigation could finally bring justice and financial relief to those harmed by a drug that was supposed to protect their health.